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Eliane Piaggio - IL-2-based therapies for the treatment of autoimmunity and cancer

  • Date de parution : 14/05/2018
  • Durée : 37 min
  • Crédits :

Résumé de la vidéo

Interleukine-2 (IL-2) is a cytokine with both immune stimulating and suppressive function. Consequently, it has been used in the clinic at high doses to stimulate the immune response against cancer and more recently it is being evaluated at low doses to block the immune response in conditions of undesired immune activation, such as autoimmunity or during GVHD. However, IL-2 can be toxic, and depending on the desired effect, IL-2 action needs to be re-direc...

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